منابع مشابه
Chronic myelodysplastic syndrome (preleukemia) with the Philadelphia chromosome.
A patient with severe anemia, reticulocytopenia, and erythroid hyperplasia of the bone marrow developed fatal acute nonlymphocytic leukemia after 3 yr. A Philadelphia chromosome with the typical 9/22 translocation t(9q +;22q-) was identified by banding techniques in a small number of bone marrow cells throughout the preleukemic phase of the illness (14%--38% of metaphases) and during the acute ...
متن کاملPreleukemia in experimental leukemogenesis.
The long latent period characteristic for both spontaneous and induced murine leukemias may reflect multiple steps in the leukemogenic process. The induction of pre leukemia represents the initial phase in leukemogenesis. A sequence of further events (that could differ qualitatively from the initiating factor) is often required for the completion of the neoplastic transformation. The presence o...
متن کاملErythropoiesis in preleukemia.
Bone marrow cells from seven patients with preleukemia and two with erythroleukemia were cultured in vitro to characterize erythropoiesis and erythropoietin responsiveness in these disorders. The methylcellulose plate technique was used to clone erythroid progenitors, and the results were compared to data obtained from studies on five healthy volunteers. Erythroid colonies formed in cultures fr...
متن کاملCellular maturation in human preleukemia.
Bone marrow cells from three preleukemic patients with prominent marrow karyotypic abnormalities were studied in liquid culture to determine if the neoplastic clones were capable of maturation. Parallel cytogenetic and cytologic studies were performed in sequentially harvested bone marrow cultures. Maturation, albeit delayed, occurred in cultures from all three patients. By 14 days of culture i...
متن کاملCHROMOSOME STUDIES OF IRANIAN MEMBERS OF TRIBE SOPHOREAE (FAMILY LEGUMINOSAE
The tribe Sophoreae sensu Polhill [9,10] is a large and diverse assemblage comprising the ancient and primitive ancestral stocks of Papilionoideae. The most frequent chromosome basic numbers in this tribe are x = 11 and x = 9 but chromosome numbers range from x = 8-14 are also known. In this study chromosome numbers and karyotype variation of Iranian members of tribe Sophoreae are reported. Ira...
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ژورنال
عنوان ژورنال: Blood
سال: 1966
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v27.6.782.782